We study coupled mechanical and biochemical changes in human disease

Principal Investigator

Dr. Tanmay Lele, Ph.D.


What is mechanobiology?

Our research is in the area of Mechanobiology. Mechanobiology is the scientific study of the mechanisms by which cell generated mechanical forces and/or the cellular mechanical environment impact cell and tissue structure and function. We are particularly interested in the mechanobiology of human diseases including cancer.


We are funded by the National Cancer Institute’s Physical Sciences and Oncology Network (PSON).

Dr. Lele became a member of the NIH study section
The Lele lab is a part of the Gulf Coast Consortia
Dr. Lele is a CPRIT scholar
Dr. Lele is Unocal Professor at TAMU
Dr. Lele's google scholar profile

8 April, 2021

Purboja Purkayastha and Kavya Pendyala published a new paper in “Molecular Biology and Evolution”

12 March, 2021

Purboja Purkayastha won the best podium presentation in ChemE annual symposium

21 September, 2020

New paper “A method for direct imaging of x-z cross-sections of fluorescent samples” accepted in Journal of Microscopy with minor revisions

1 September, 2020

Dr. Yuan Li has become Assistant Professor at Xi’an Jiaotong University where he will pursue research in Biomechanics

10 December, 2021

American Institute of Physics showcases new paper on “Viscous coupling of the compliant nucleus” in a Scilight article

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