Our research is in the area of Mechanobiology. We are interested in the molecular mechanisms by which cell generated mechanical forces and associated signaling pathways enable cell and tissue functions. Current research projects in the laboratory include quantitative measurements of nuclear forces, the effect of mechanical stresses on nuclear functions and gene expression, cellular adaptation to mechanical properties of the extracellular matrix, and the mechanics of tissue development

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October 23: New paper “Nuclear size changes caused by local motion of cell boundaries unfold the nuclear lamina and dilate chromatin and intranuclear bodies” accepted in Soft Matter.