Mechanobiology

We study coupled mechanical and biochemical changes in human disease

Principal Investigator

Dr. Tanmay Lele, Ph.D.
Professor

 

Ph.D. Students

Christina Dubell

Ph.D. Students

Lopamudra Ghosh

Ph.D. Students

Mohammad Mohajeri

Ph.D. Students

Ting-Ching Wang

Ph.D. Students

Ryan Blanchard

Ph.D. Students

Te-An (Ann) Chen

Lab Coordinator

Kavya Pendyala

What is mechanobiology?

Our research is in the area of Mechanobiology. Mechanobiology is the scientific study of the mechanisms by which cell generated mechanical forces and/or the cellular mechanical environment impact cell and tissue structure and function. We are particularly interested in the mechanobiology of human diseases including cancer.

Recognition

Dr. Lele is a Fellow of the American Institute of Medical and Biological Engineering

Dr. Lele is a member of the BMBI NIH study section

Dr. Lele is a Fellow of the Biomedical Engineering Society

Dr. Lele is a CPRIT scholar

Dr. Lele is Unocal Professor at TAMU

Dr. Lele's google scholar profile

November 2024

Paper on nuclear wrinkling as a marker of cancer accepted in npj Precision Oncology

October 2024

Paper on nuclear drop model in mechanotransduction accepted in Nature Communications

August 2024

New paper published in PNAS on the interaction between genetic variation and cellular sensing of ECM stiffness

April 2024

New paper published on indirect control of nucleocytoplasmic transport by mechanical stimuli in Journal of Cell Biology

Feb 2024

Paper published on Cell Mechanotransduction in Biomaterials

Associations with