News & Events

The University of Florida Office of Research awards Qiao Zhang and VJ Tocco $400 each for support in traveling to the AIChE and BMES annual meetings, respectively. Congratulations!

May 2017: The Journal of Cellular Physiology designates our recent paper, “The nucleus is irreversibly shaped by motion of cell boundaries in cancer and non-cancer cells,” the spotlight article (in press).

Our recent PNAS publication “On the Ultra-Donut Topology of The Nuclear Envelope” was selected as a feature topic on Math in the Media (11/2016) by American Mathematical Society.

Feb. 2017, Qiao Zhang presented his poster: “Coordinated dynamics of RNA splicing speckles in the nucleus” in Physical Science of Cancer Gordon Research Conference, Galveston, TX.

Jan. 2017, Qiao Zhang won the Office of Research Award for his trip to attend the Physical Science of Cancer, Gordon Research Conference in Galveston, Texas. Congratulations.

Dec, 2016, new paper: “The mammalian LINC complex regulates genome transcriptional responses to substrate rigidity” is published online in Scientific Reports.

November, 2016, Varun Aggarwal successfully defended his thesis :”Mathematical Modeling of Cytoplasmic Gradients: Sampling by the Moving Nucleus.” Congratulations, Dr. Aggarwal.

October, 2016, Srujana Neelam’s article, “Vertical uniformity of cells and nuclei in epithelial monolayers”, Scientific Reports, 2016, has been recommended in F1000Prime as being of special significance in its field. Congratulations!

July, 2016, Ian Kent successfully defended his thesis, “­­Interphase Microtubules: Mechanics and Nuclear Interactions”. Congratulations, Dr. Kent!  

July, 2016, new paper: “On the Ultra-Donut Topology of The Nuclear Envelope” accepted for publication in Proceedings of the National Academy of Sciences.

April, 2016, Samer Alam successfully defended his thesis, “Nuclear Forces and Gene Expression: an Analysis in Fibroblasts”. Congratulations!    

March, 2016, new paper: “Transient Pinning and Pulling: A Mechanism for Bending Microtubules” was published online in PLOS ONE.

February, 2016, Qiao Zhang’s article “Coordinated dynamics of RNA splicing speckles in the nucleus” has been selected to be featured on the cover of the Journal of Cellular Physiology. Congratulations!

January, 2016, new paper: “Concentration sensing by the moving nucleus in cell fate determination: a computational analysis” accepted for publication in PLOS ONE.

December, 2015, new paper: “An unresolved LINC in the nuclear envelope” accepted for publication in Cellular and Molecular Bioengineering.

November, 2015, new paper: “Vertical uniformity of cells and nuclei in epithelial monolayers” accepted for publication in Scientific Reports.

October, 2015, new paper: “Coordinated dynamics of RNA splicing speckles in the nucleus” accepted for publication in Journal of Cellular Physiology.

August, 2015, simulation movie of cell spreading and nuclear flattening from Yuan Li’s article has been selected as a Featured Video in Biophysical Journal. Congratulation!

July, 2015, new paper: “Moving cell boundary drives nuclear flattening during cell spreading” accepted for publication in Biophysical Journal.

May, 2015, Srujana Neelam’s article, “Direct force probe reveals the mechanics of nuclear homeostasis in the mammalian cell”, PNAS, 2015, has been recommended in F1000Prime as being of special significance in its field. Congratulations!

April, 2015, Samer Alam’s article “The nucleus is an intracellular propagator of tensile forces in NIH 3T3 fibroblasts” has been selected for inclusion in the ‘In This Issue’ section of JCS. Congratulations!

March, 2015, new paper: “A direct force probe reveals the mechanics of nuclear homeostasis in the mammalian cell” accepted for publication in Proceedings of the National Academy of Sciences.

March, 2015, new paper: “The nucleus is an intracellular propagator of tensile forces in NIH 3T3 fibroblasts” accepted for publication in the Journal of Cell Science.

January, 2014, T.J. Chancellor’s article “Actomyosin tension exerted on the nucleus through nesprin-1 connections influences endothelial cell adhesion, migration, and cyclic strain-induced reorientation”, Biophysical Journal, 2010, has been selected for F1000Prime as being of special significance in its field. Congratulations!

November, 2013, David Lovett successfully defended his thesis, “Nuclear Shape Control in Fibroblasts”. Congratulations!

November, 2013, new paper: “Actomyosin pulls to advance the nucleus in a migrating tissue cell” accepted for publication in Biophysical Journal.

November, 2013, Nandini Shekhar, a recent MS graduate has accepted a professional position as a Scientific Associate II with Novartis Institute for Biomedical Research. Congratulations!

August, 2013, Jiyeon Lee, a recent PhD graduate has become a faculty member in Korea Institute of Science and Technology.  Her research area is in Nano-biotechnology. Congratulations!

August, 2013, New paper: “Dendritic cell activation is influenced by cyclic mechanical strain when cultured on adhesive substrates” accepted for publication in Biomaterials.

May, 2013, New paper: “Fluctuating Motor Forces Bend Growing Microtubules” accepted for publication in Cellular and Molecular Bioengineering.

March, 2013, David Lovett received the Best Graduate Student Poster Award at the University of Florida Society for Biomaterials Annual Meeting.

January, 2013, New paper: “Modulation of nuclear shape by substrate rigidity” accepted for publication in Cellular and Molecular Bioengineering.

October, 2012, Nandini Shekhar’s abstract “Effect of Microtubule Motors on Microtubule Mechanics in Living Cells” was rated as one of the top abstracts in the Cellular and Molecular Bioengineering Track submitted for presentation at the 2012 BMES meeting in Atlanta,GA.

October, 2012, Dr. Jun Wu has accepted a postdoctoral research position at the University of Illinois at Urbana-Champaign.

October, 2012, Nandini Sekhar has accepted a scientist position at the Massachusetts Institute of Technology.

August, 2012, New paper: “FRAP Analysis: Accounting for Bleaching during Image Capture” published in PLOS ONE.

May, 2012, David Lovett awarded the Ruska Award at the Southeastern Microscopy Society conference (SEMS is an affiliate of the Microscopy Society of America).

April, 2012, Review article published: “Investigation of in vivo Microtubule and Stress Fiber Mechanics with Laser Ablation” in Integrative Biology.

Spring, 2012, Jun Wu’s research on “Microtubule Mechanics and Centrosome Positioning” highlighted in UF Explore magazine.

Spring, 2012, Jun Wu’s article “Effects of Dynein on Microtubule Mechanics and Centrosome Positioning” won the Graduate Publication Award, silver medal at the Department of Chemical Engineering, University of Florida.

February, 2012, TJ Chancellor awarded the best presentation award in the Biological Science Session at the 13th Chemical Engineering Graduate Symposium, University of Florida.

December, 2011, Jun Wu’s article “Effects of dynein on microtubule mechanics and centrosome positioning” published in Molecular Biology of the Cell.

October, 2011, Jun Wu’s article “How Dynein and Microtubules Rotate the Nucleus” highlighted in Journal of Cellular Physiology.

October, 2011, Jun Wu awarded the NSF Travel Award at ASME 2011 International Mechanical Engineering Congress & Exposition.

February, 2011, Jun Wu won the best presentation Award in Biological Science Session at the 12th Chemical Engineering Graduate Symposium, University of Florida.

October, 2010, Jiyeon Lee chosen as a finalist for an award presentation at the AICHE annual meeting.

July, 2010, TJ’s article “Actomyosin Tension Exerted on the Nucleus through Nesprin-1 Connections Influences Endothelial Cell Adhesion, Migration, and Cyclic Strain-Induced Reorientation” chosen as a featured article in Biophysical Journal.

May, 2010, Jiyeon receives her PhD degree, the first doctorate graduated from the Lele Lab. Congratulations, Dr. Lee!

October, 2009, David Lovett joins the Lele Lab as a PhD student.

October, 2007, Jun joins the Lele Lab as a PhD student.