We are located in the Department of Chemical Engineering at the University of Florida.
Cells in our body perform complex tasks, including movement across tissues, adhesion to polymeric scaffolds in the body and the sensing of chemical and mechanical signals. These complex processes depend in large part on the intracellular cytoskeleton. Specialized ‘motor’ proteins that convert chemical energy into mechanical work associate and move along the polymeric cytoskeleton enabling critical cell functions including intracellular mechanical force generation. We are interested in how the cytoskeleton and associated motor proteins generates forces inside the living cell. This work has applications in understanding diseases of the cardiovascular and muscular system, as well as cancer. We are also developing new biomaterials and nanotechnologies for characterizing and controlling cellular forces.
News & Events
September 11: New paper “ A skeptic’s guide to bacterial mechanosensing ” accepted in Journal of Molecular Biology.
July 07: New paper “ Mechanical stabilization of the glandular acinus by linker of nucleoskeleton and cytoskeleton complex ” accepted in Current Biology.
June 26: New paper “ A Mutation in Histone H2B Represents a New Class of Oncogenic Driver” accepted in Cancer Discovery.
June 12: Aditya Katiyar received the travel award for the Summer Training Program at Center for the Physics of Living Cells (CPLC), University of Illinois Urbana-Champaign.